Islets of Hope for persons with prediabetes

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Article by Lahle Wolfe, 03/25/2006.  For reprint information e-mail


American Diabetes Association: What is prediabetes?

NIH Publication:  Insulin Resistance and Pre-diabetes

More Information about Metabolic Disorders

Prediabetes & Diabetes Prevention Studies & Research

Insulin Resistance and Insulin Resistance Syndrome (IRS)

Metabolic Syndrome (formerly called "Syndrome X" which is now considered outdated) is the same thing as Insulin Resistance Syndrome (IRS)

Confused?  See our Chart Comparison between Insulin Resistance, Insulin Resistance Syndrome (IRS), Prediabetes, Types 1 and 2 Diabetes, and Gestational Diabetes detailing the symptoms, diagnosis, treatment, and prognosis of these major metabolic disorders.

Lifestyle Changes -  Diet, Exercise, Sports, Stress Management

low gi guide to metabolic disorders
The New Glucose Revolution
Pocket Guide to Metabolic Syndrome
The latest medical research clearly confirms that the glycemic index (GI)—an easy-to-understand ranking of foods based on their effect on blood glucose levels—is vitally important for heart health and the prevention of the Metabolic Syndrome (aka Syndrome X and insulin resistance). Slowly... Read more

Did You Know?

... that the diabetes drug Glucophage (metformin), a biguanide, reduced the risk of diabetes in those with prediabetes but was less successful than simply losing weight and increasing activity? (NIH DPP Study) See our Lifestyles section to learn how you can improve your health without medication.

... that prediabetes increases your risk of getting type 2 diabetes and of having heart disease or a stroke?

... that prediabetes can be reversed without insulin or medication by losing a modest amount of weight and increasing your physical activity?  

... that an international expert committee of the American Diabetes Association recently redefined the criteria for prediabetes, lowering the blood sugar level cut-off point for pre-diabetes?

Approximately 20% more adults are now believed to have this condition and may develop diabetes within 10 years if they do not exercise or maintain a healthy weight.

Life Without Bread
Life Without Bread
First Sentence: CONTRARY TO CURRENT POPULAR WISDOM, it is carbohydrates, not fat, that contribute to many dietary related diseases.


islets of hope diabetes medical library                        main Medical Information page
Metabolic disorders                                                                               
  main Metabolic Disorders page

Metabolic disorders associated with prediabetes
previously known as impaired fasting glucose (IFG) or impaired glucose tolerance (IGT)

Prediabetes and insulin resistance
Diabetes types 1 and 2 and insulin resistance

Other metabolic disorders that may be associated with insulin resistance

the insulin resistance diet
The Insulin Resistance Diet
The Insulin-Resistance Diet: How to Turn Off Your Body's Fat-Making Machine recommends a well-researched health program based on the relationship between insulin and fat. While low-fat foods are a part of the plan, Cheryle R. Hart and Mary Kay Grossman (doctors at the Women's Workshop, a medical... Read more

Prediabetes and insulin resistance

If you have prediabetes, you probably have been insulin resistant for some time without knowing it.  You also have a higher risk of developing type 2 diabetes. Studies have shown that most people with prediabetes go on to develop type 2 diabetes within 10 years.  But onset of diabetes is not inevitable, in fact, you can often reverse prediabetes and insulin resistance simply by losing weight and exercising.

Even losing a modest 5-7% of excess body weight can have a dramatic and positive impact on reducing the risk of developing type 2 diabetes.  For an overweight person that weighs 200 lbs, that means losing only 10 or 15 lbs.

Diabetes types 1 and 2 and insulin resistance

Type 2 diabetes is form of diabetes that develops when the body does not respond properly to insulin. At first, the pancreas keeps up with the added demand by producing more insulin, however, it loses the ability to secrete enough insulin in response to meals. When blood glucose levels cannot be controlled with lifestyle and medication, injection of insulin may become necessary.

In most forms of type 1 diabetes, the pancreas makes no insulin at all, but insulin resistance can also occur in people who have type 1 diabetes, especially if they are over weight. For those who take insulin injections, repeatedly using the same injection site can cause damage to surrounding tissues that makes the area less sensitive to insulin.  Rotating injection and canula sites is important to help prevent this localized insulin resistance 

Other metabolic disorders that may be associated with prediabetes and insulin resistance

Other conditions may cause, be exacerbated, or result from insulin resistance.  It is important for your doctor to take a complete medical history for you, and for family members as some disorders can be hereditary in nature.  Be sure to tell your doctor if any family members have autoimmune disorders, metabolic disorders, or other serious health problems like cancer, heart disease, or high blood pressure or cholesterol.

In addition to the potential for diabetes, other disorders that may also be present with either insulin resistance, or with IRS include:

An estimated 41 million Americans have the condition identified since 2002 as prediabetes, which, if left unchecked, inevitably will lead to full-blown diabetes. From one of the world's leading diabetes "patient-experts," this first-ever practical guide offers fifty essential, informative ideas and simple steps to help this vast and rapidly growing constituency manage their condition and thereby reduce their chances of developing full-blown diabetes. Prediabetes clearly explains what readers can do today, no matter what their age, and whether or not they have a family history of diabetes, a severe weight problem, or are members of an ethnic group at high risk-including Hispanics, Native Americans, African Americans, and Pacific Islanders. Helpful drawings and graphs are featured throughout in this new, revised edition.

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