Islets of Hope         What is intermediate-acting insulin?

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Want help determining how to calculate your need for insulin? First, be sure to check with your doctor but you can also use Insulin Pumper's insulin calculating tool to better understand how your doctor might  determine your need for insulin.

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Description of Types of Injected Insulin Available
-- Animal insulin
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Chemically modified insulins
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Non-hexameric insulins
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Aspart insulin
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Shifted isoelectric point insulin
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Detemir insulin
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Inhaled Insulin

Intermediate-Acting Insulin

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Insulin is a hormone normally produced in the body by the beta islets cells of the pancreas that aids in the processing of food into energy that the body can use. There are many types of insulin.

Definition: Intermediate-acting insulin refers to a type of insulin that does not work as quickly as rapid or fasting-acting insulin.   Intermediate-acting insulins are insulin analogues (man-made) that are used to treat diabetes mellitus.  These insulins are cloudy in color and often referred to as "NPH" and include:

  • Humulin-N - Humulin-N Pen - (NPH human insulin (rDNA ORIGIN) isophane suspension 100 UNITS per ML (U-100))

  • Novolin-N - Generic Name: insulin isophane.  Brand Names: Humulin N, Humulin N Pen, Iletin II NPH Pork, Insulin Purified NPH Pork, Novolin N, Novolin N Innolet, Novolin N PenFill

Intermediate insulin enters the bloodstream about 2 to 4 hours after it is injected and peaks 4-10 hours later.  It is effective for about 12 to 16 hours.

Intermediate-acting insulin is insulin mixed with something that makes the body absorb the insulin more slowly.  While an allergy to insulin itself is rare, some people may be allergic to the buffering agents mixed in with intermediate-acting insulin.

All persons with the juvenile form of type 1 diabetes need to take insulin to live.  

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Page Updated 07/24/2007