Islets of Hope  complications of diabetes

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Edited by Lahle Wolfe

Source

Excerpts with Permission from; NIH Publication No. 04–4348, December 2003


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Gastroparesis Information Links

A virtual on-line center for education/counseling of patients with severe motility disorders

Detailed information about Erythromycin

Information on Motility

Learn about Gastric Emptying Studies

About.com - Gastroparesis - The stomach contracts to empty itself of food and liquid, contracting about three times a minute and emptying within 90-120 minutes after eating. With gastroparesis, the contractions are sluggish or less frequent, and stomach emptying is delayed. Gastroparesis is most often a complication of type 1 diabetes. At least 20 percent of people with type 1 diabetes develop gastroparesis. It also occurs in people with type 2 diabetes, although less often.


Gastroparesis Support Links

Gastroparesis Patient Organization for Cures and Treatment, Inc.

Yahoo - Online support group for parents of children with GP.

 

islets of hope diabetes medical library                       back to main "Complications" page

Diabetes Complications
Symptoms, Causes & Treatment

Diabetic Gastroparesis
(Delayed Gastric Emptying)


Mini Site Index

What is Gastroparesis?
Signs and Symptoms
Complications of Gastroparesis
Major Causes of Gastroparesis
Diagnosis
Treatment
Points to Remember

Also, see "Cyclic Vomiting Syndrome" and "Diabetic Neuropathy."

What is Gastroparesis?

Pronounced gas-tro-par-EES-is, "gastro" means stomach and "paresis means weakness. Gastroparesis is simply a weak stomach and the most common cause of gastropareesis is diabetes. Gastroparesis, also called delayed gastric emptying, is a disorder in which the stomach takes too long to empty its contents. It often occurs in people with type 1 diabetes or type 2 diabetes.

Gastroparesis happens when nerves to the stomach are damaged or stop working. The vagus nerve controls the movement of food through the digestive tract. If the vagus nerve is damaged, the muscles of the stomach and intestines do not work normally, and the movement of food is slowed or stopped.

Diabetes can damage the vagus nerve if blood glucose levels remain high over a long period of time. High blood glucose causes chemical changes in nerves and damages the blood vessels that carry oxygen and nutrients to the nerves.

Illustration of the digestive system

The digestive system

   


Signs and Symptoms

Signs and symptoms of gastroparesis include the following:

  • heartburn
  • nausea
  • vomiting of undigested food
  • an early feeling of fullness when eating
  • weight loss
  • abdominal bloating
  • erratic blood glucose levels
  • lack of appetite
  • gastroesophageal reflux
  • spasms of the stomach wall

These symptoms may be mild or severe, depending on the person.


Complications of Gastroparesis

If food lingers too long in the stomach, it can cause problems like bacterial overgrowth from the fermentation of food. Also, the food can harden into solid masses called bezoars that may cause nausea, vomiting, and obstruction in the stomach. Bezoars can be dangerous if they block the passage of food into the small intestine.

Gastroparesis can make diabetes worse by adding to the difficulty of controlling blood glucose. When food that has been delayed in the stomach finally enters the small intestine and is absorbed, blood glucose levels rise. Since gastroparesis makes stomach emptying unpredictable, a person's blood glucose levels can be erratic and difficult to control.

   


Major Causes of Gastroparesis

Gastroparesis is most often caused by

  • diabetes
  • postviral syndromes